Lipodox® (generic doxorubicin hydrochloride liposome injection): in vivo efficacy and bioequivalence versus Caelyx® (doxorubicin hydrochloride liposome injection) in human mammary carcinoma (MX-1) xenograft and syngeneic fibrosarcoma (WEHI 164) mouse models
نویسندگان
چکیده
منابع مشابه
Flow Injection Spectrophotometric determination of Doxorubicin Hydrochloride in Urine samples
A simple and fast FI colorimetric procedure for determination of doxorubicin hydrochloride (DXH) was proposed. It is based on the redox reaction between iron (III) and DXH, resulting in an intensely red colored complex in the presence of 1, 10-orthophenantroline which can be followed by spectrophotometric measurement at λmax= 510 nm. This is an automatic way to determine doxorubicin hydrochlori...
متن کاملCompatibility and stability of vincristine sulfate, doxorubicin hydrochloride, and etoposide in 0.9% sodium chloride injection.
dministering cancer chemotherapy by continuous intravenous infusion (CIVI) has several potential advantages over administration by short intravenous infusions1 and has been facilitated by the development of portable infusion pumps.2 In a study by Wilson et al.,3 the EPOCH regimen—etoposide, prednisone, vincristine, cylophosphamide, and doxorubicin—was shown to be highly effective and well toler...
متن کاملDirect injection of liposome-encapsulated doxorubicin optimizes chemomyectomy in rabbit eyelid.
PURPOSE Doxorubicin chemomyectomy presently represents the only permanent, nonsurgical treatment for blepharospasm and hemifacial spasm. The major deterrent to an otherwise extremely effective treatment protocol is the development in patients of localized inflammation, discomfort, and skin injury over the injection site. As a potential alternative therapy, Doxil (Sequus, Menlo Park, CA), a lipo...
متن کاملPegylated liposome-encapsulated doxorubicin and cisplatin enhance the effect of radiotherapy in a tumor xenograft model.
Concomitant chemotherapy and radiotherapy (CCRT) has recently been shown to improve treatment outcome in a range of solid tumors. Pegylated liposomes have the potential to target drugs directly to tumors and may increase the efficacy and reduce the toxicity of CCRT by selectively delivering radiosensitizing agents to tumor, as opposed to normal, tissues. In these studies, we have assessed CCRT ...
متن کاملAdriamycin RDF doxorubicin hydrochloride for injection, USP FOR INTRAVENOUS USE ONLY WARNING
WARNING 1. Severe local tissue necrosis will occur if there is extravasation during administration (see DOSAGE AND ADMINISTRATION). Doxorubicin must not be given by the intramuscular or subcutaneous route. 2. Myocardial toxicity manifested in its most severe form by potentially fatal congestive heart failure may occur either during therapy or months to years after termination of therapy. The pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Cancer
سال: 2017
ISSN: 1471-2407
DOI: 10.1186/s12885-017-3377-3